The U.S. State Department has issued a comprehensive security alert covering the Middle East, warning that heightened regional tensions could result in retaliatory actions by Iran or its proxy groups targeting American citizens and interests globally.

Official guidance warns travelers to prepare for potential flight disruptions, sudden airspace closures, and unpredictable security shifts. Authorities emphasized that Iranian retaliation or affiliated operations could extend beyond the region, urging U.S. citizens, businesses, and institutions worldwide to maintain heightened vigilance.